Inapparent Lun G Involvemen T in Patients with the Subacut E Juvenil E Typ E of Paracoccidioidomycosis
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چکیده
T h r e e p a t i e n t s w i t h th e d i a g n o s i s of s u b a c u t e j u v e n i le p a r a c o c c i d i o i d o m y c o s is who , a t th e t im e o f the i r f i rs t v i s i t , h a d n o s i g n s o r s y m p t o m s o f l u n g i n v o l v e m e n t , were s t u d i e d . I n i t i a l l y th e d i a g n o s i s w as c o n f i r m e d b y th e o b s e r v a t i o n o f P . b r a s i l i e n s i s i n b i o p s y m a t e r i a l o b t a i n e d f ro m c l i n i c a l l y i n v o l v e d l y m p h a d e n o p a t h i e s . T h e l u n g X r a y s d o n e i n a l l p a t i e n t s, d i d no t revea l p a t h o l o g ic c h a n g e s , a l t h o u g h i t w a s p o s s i b l e t o obse rv e a n d i so la t e th e f u n g u s f ro m s p u t u m s a m p l e s o b t a i n e d f rom th e thre e pa t i en t s . T h i s fac t re in fo rce s th e p u l m o n a r y g e n e s i s o f th e m y c o s i s a n d proof s th e e x i s t e n c e o f a p u l m o n a r y p r i m a r y i n fec t i on , e v e n i n p a t i e n t s w i t h the j u v e n i l e m a n i f e s t a t i o n s , i n w h o m th e l u n g c o m p o n e n t i s o b s c u r e d b y th e p red o m i n a n t l y m p h n o d e i n v o l v e m e n t .
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